Transduction of Recombinant M3-p53-R12 Protein Enhances Human Leukemia Cell Apoptosis
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چکیده
منابع مشابه
Transduction of Recombinant M3-p53-R12 Protein Enhances Human Leukemia Cell Apoptosis
Tumor suppressor protein p53 plays important roles in initiating cell cycle arrest and promoting tumor cell apoptosis. Previous studies have shown that p53 is either mutated or defective in approximately 50% of human cancers; therefore restoring normal p53 activity in cancer cells might be an effective anticancer therapeutic approach. Herein, we designed a chimeric p53 protein flanked with the ...
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ژورنال
عنوان ژورنال: Journal of Cancer
سال: 2016
ISSN: 1837-9664
DOI: 10.7150/jca.15155